The Siberian Scientific Medical Journal
№ 3 / 2014 / 108-113

Regularities of formation of glaucomatous optic neuropathy from latent to advanced stage of the disease

Author Affiliations


Purpose: to determine regularities and mechanisms of structural and functional changes in neuro-retinal complex in formation of glaucomatous optic neuropathy. Methods: 94 people with early stages of glaucoma were examined with spectral optical tomography, chromatic methods of perimetry, electroretinography and electrophysiological examination. Results: Formation of glaucomatous neuropathy begins from deformation of dendrites of ganglion retinal cells, and then change of their axons occurs, which is confirmed by volume index increase of ganglion retinal complex global loss and following decrease of neural fiber thickness.

Key words

OCT diagnostics of glaucoma, complex of ganglion cells, latent stage of glaucoma
About Authors (Correspondence):

Yureva T.N. – doctor of medical sciences, professor of the chair for ophthalmology, vice director for scientific work, e-mail:

Pyatova Yu.S. – ophthalmologist, e-mail:

Khudonogov А.А. – candidate of medical sciences, assistant of the chair for ophthalmology

Shchuko А.G. – doctor of medical sciences, professor, director, head of the chair for ophthalmology

Full Text

Received: 09/02/2015