Preoperative medication for glaucoma and cataract: problems of choice

Abstract

There have been multiple scientific publications reporting of cases and post-hoc analysis of relationship between the prostaglandin analogues (PA) use and postoperative macular edema development in patients underwent cataract surgery. The purpose of research is to compare effects of different groups of antihypertensive drugs on condition of central retina in patients with primary open-angle glaucoma (POAG) after phacoemulsification of cataract (PC) and combined surgeries for cataract and glaucoma. Material and methods. Analysis was carried out with data on 36 patients (49 eyes) underwent the cataract surgery on the top of POAG: group I – 12 patients (15 eyes) who were receiving antihypertensive therapy of PA before and after PC; group II – 10 patients (11 eyes) who were receiving PA therapy prior to combined surgery for cataract and glaucoma (PA were cancelled during postoperative period); group III – 14 patients (25 eyes) who were receiving antihypertensive therapy of any drug group excluding PA before and after PC. Results. The thickness in central retina of all 3 groups` patients was comparable both before and after the surgery, differences were statistically insignificant. Cross-group measurement results were also statistically insignificant. Conclusion. Findings of the study have not identified any convincing evidence that would support a change of antihypertensive drugs against POAG as a preparation for cataract surgery and during early postoperative period to reduce the risk of macular edema. The use of prostaglandins analogs does not result in conspicuous changes in thickness of macula zone of retina during postoperative period.

Key words

primary open-angle glaucoma and cataract, analogs of prostaglandins, macular edema, retina thickness

References

Nesterov A.P. Glaukoma. Moscow: Meditsinskoe informatsionnoe agentstvo, 2014. 360 p. [In Russian].
National glaucoma guide: for practitioners. Eds. E.A. Egorov, Yu.S. Astakhov, V.P. Erichev. Moscow: GEOTAR-Media, 2015. 456 p. [In Russian].
Neroev V.V. Ophthalmological personnel and their role in the organization of ophthalmological care in the Russian Federation: rep. XI Russian national ophthalmological forum. Moscow, 2018. [In Russian].
Neroev V.V. Vision Disability in the Russian Federation. Belye nochi - 2017: rep. Russian ophthalmological congress, Saint Petersburg, 2017. [In Russian].
European Glaucoma Society. Terminology and guidelines for glaucoma. 4th edition. Savona: Italy PubliComm, 2014. 71 p.
Altuntas Ö., Yuksel N., Karabas V.L., Demirci G. Cystoid macular edema associated with latanoprost after uncomplicated cataract. Eur. J. Ophthalmol. 2005; 15 (1): 158-161. doi: 10.5301/EJO.2008.539.
Miyake K., Ibaraki N. Prostaglandins and cystoid macular edema. Surv. Ophthalmol. 2002; 47 (1): 203–218. doi: 10.1016/s0039-6257(02)00294-1.
Arcieri E.S., Santana A., Rocha F.N., Guapo G.L., Costa V.P. Blood aqueous barrier changes after the use of prostaglandin analogues in patients with pseudophakia and aphakia: a 6-month randomized trial. Arch. Ophthalmol. 2005; 123 (2): 186-192. doi: 10.1001/archopht.123.2.186.
Chang J.H., McCluskey P., Missotten T., Ferrante P, Jalaludin B, Lightman S. Use of ocular hypotensive prostaglandin analogues in patients with uveitis: does their use increase anterior uveitis and cystoid macular oedema? Br. J. Ophthalmol. 2008; 92 (7): 916–921. doi: 10.1136/bjo.2007.131037.
Schumer R.A., Camras C.B., Mandahl A.K. Latanoprost and cystoid macular edema: is there a causal relation? Curr. Opin. Ophthalmol. 2000; 11 (2): 94–100. doi: 10.1097/00055735-200004000-00005.
Furuichi M., Chiba T., Abe K., Kogure S, Iijima H., Tsukahara S., Kashiwagi K. Cystoid macular edema associated with topical latanoprost in glaucomatous eyes with a normally functioning blood-ocular barrier. J. Glaucoma. 2001; 10 (3): 233-236. doi: 10.1097/00061198-200106000-00016.
Miyake K., Ibaraki N., Goto Y., Oogiya S., Ishigaki J., Ota I., Miyake S. ESCRS Binkhorst lecture 2002: pseudophakic preservative maculopathy. J. Cataract Refract. Surg. 2003; 29 (9): 1800-1810. doi: 10.1016/s0886-3350(03)00560-1.
Henderson B.A., Kim J.Y., Ament C.S., Ferrufino-Ponce Z.K., Grabowska A., Cremers S.L. Clinical pseudophakic cystoid macular edema. Risk factors for development and duration after treatment. J. Cataract Refract. Surg. 2007; 33 (9): 1550-1558. doi: 10.1155/2017/4625730/
Moroi S.E., Gottfredsdottir M.S., Schteingart M.T., Elner S.G., Lee C.M., Schertzer R.M., Abrams G.W., Johnson M.W. Cystoid macular edema associated with latanoprost therapy in a case series of patients with glaucoma and ocular hypertension. Ophthalmology. 1999; 106 (5): 1024–1029. doi 10.1016/S0161-6420(99)00528-X.
Astakhov S.Yu., Astakhov Yu.S., Gobedzhishvili M.V. The influence of prostaglandin analogs on the retinal thickness after phacoemulsification with intraocular lens implantation in primary open-angle glaucoma patients. Oftalmologiceskie vedomosti = Ophthalmology journal. 2014; 7 (3): 73-76. [In Russian].
Glaucoma. National manual. Ed. E.A. Egorov. Moscow: GEOTAR Media, 2013. 824 p. [In Russian].
Miyake K., Ota I., Maekubo K., Ichihashi S., Miyake S. Latanoprost accelerates disruption of the blood-aqueous barrier and the incidence of angiographic cystoid macular edema in early postoperative pseudophakias. Arch. Ophthalmol. 1999; 117 (1): 34–40. doi 10.1001/archopht.117.1.34.
Schumer R.A., Camras C.B., Mandahl A.K. Putative side effects of prostaglandin analogs. Surv. Ophthalmol. 2002; 47: S219. doi 10.1016/s0039-6257(02)00328-4.
Yeh P.C., Ramanathan S. Latanoprost and clinically significant cystoid macular edema after uneventful phacoemulsification with intraocular lens implantation. J. Cataract Refract. Surg. 2002; 28 (10): 1814–1818. doi: 10.1016/s0886-3350(02)01334-2.
Wand M., Gaudio A.R. Cystoid macular edema associated with ocular hypotensive lipids. Am. J. Ophthalmol. 2002; 133 (3): 403-405. doi: 10.1016/s0002-9394(01)01411-8.
Warwar R.E., Bullock J.D., Ballal D. Cystoid macular oedema and anterior uveitis associated with latanoprost use. Experience and incidence in a retrospective review of 94 patients. Ophthalmology. 1998; 105 (2): 263–268. doi: 10.1016/s0161-6420(98)92977-3.
Ioshin I.E., Tolchinskaya A.I., Kalinnikov Yu.Yu., Ozderbaeva A.A. Prevention of macular edema in cataract phacoemulsification. Rossiyskiy oftal'mologicheskiy zhurnal = Russian Ophthalmological Journal. 2014; (2): 21–26. [In Russian].
Avetisov S.E., Erichev V.P., Kozlova I.V., Kosova Dzh.V. Effect of prostaglandin analogues on the morphofunctional characteristics of the retina in patients with glaucoma after phacoemulsification. Glaukoma = Glaucoma. 2017; 16 (1): 75-84. [In Russian].

About Authors (Correspondence):

Gusarevich A.A., e-mail: annagusarevich@gmail.com

Full Text

snmzh_3-2020_gusarevich_i_dr.pdf

Received: 30/06/2020

Accepted: 30/06/2020