The Siberian Scientific Medical Journal
 
 
№ 2 / 2014 / 24-28

Peculiarities of decorin expression in heterotopic endometrium at two forms of genital endometriosis

Author Affiliations

Abstract

To study the expression of dermatan sulfate proteoglycan decorin in two forms of genital endometriosis. Material and methods: 49 samples of surgical specimens of 14 patients with ovarial endometriosis and 3 women with adenomyosis; immunohistochemical two-step streptavidin-biotin method. The statistically significant more pronounced expression of dermatan sulfate proteoglycan decorin in the cellular elements of cytogenic stroma was demonstrated compared with samples of adenomyosis (p < 0.0001), and samples of endometrial cysts in women using combined oral contraceptives for 6 months before surgery. No significant differences in the expression of decorin in the endometrioid fibrous stroma of two forms of genital endometriosis were found.

Key words

automatic image analysis, adenomyosis, decorin, immunohistochemistry, ovarial endometriosis
References
About Authors (Correspondence):

Marinkin I.O. - doctor of medical sciences, professor, head of the chair for obstetrics and gynecology, rector
Aidagulova S.V. - doctor of biological sciences, professor, head of the laboratory for cellular biology and fundamental basis of reproduction, e-mail: a_sv@ngs.ru
Timofeeva Yu.S. - 6-year student of the chair for general medicine
Arkhipov S.A. - doctor of biological sciences, head of the laboratory for cytology and cell cultures
Kuleshov V.M. - doctor of medical sciences, professor of the chair for obstetrics and gynecology
Avdiyuk G.A. - candidate of medical sciences, professor assistant of the chair for obstetrics and gynecology
Kucherenko S.G. - candidate of medical sciences, associate professor of the chair for obstetrics and gynecology
Piven L.A. - candidate of medical sciences, associate professor of the chair for obstetrics and gynecology
 

Full Text

Received: 09/02/2015