Cytotoxic necrotizing factor of Yersinia Pseudotuberculosis, pathogen of far eastern scarlet-like fever
Author Affiliations1FSBI «RI for Epidemiology and Microbiology named after G.P. Somov» of SB RAMS 690087, Vladivostok, Selskaya str., 1
2Institute of Epidemiology and Microbiology n.a. N.F. Gamaleya 123098, Moscow, Gamaleya str., 18
3Institute of Protein Research RAS 142290, Pushchino, Institutskaya str., 4; State Research Center of Applied Microbiology and Biotechnology of Minzdrav of Russia 142279, Moscow reg., Serpukhov district, village Obolensk
4FSBI «RI for Epidemiology and Microbiology named after G.P. Somov» of SB RAMS 690087, Vladivostok, Selskaya str., 1
5Institute of Epidemiology and Microbiology n.a. N.F. Gamaleya 123098, Moscow, Gamaleya str., 18
6FSBI «RI for Epidemiology and Microbiology named after G.P. Somov» of SB RAMS 690087, Vladivostok, Selskaya str., 1
Abstract
The materials on isolation and purification of the cytotoxic necrotizing factor of Y. pseudotuberculosis, its identification by mass spectrometry, a molecular genetic characterization of two domains of its toxin gene, including functionally significant, in strains of bacteria isolated from patients, small rodents and the environment in the Russian Federation have been introduced in the article.
Key words
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About Authors (Correspondence):
Persiyanova E.V. – candidate of biological sciences, senior researcher of the laboratory of ecology of pathogenic bacteria, e-mail: Helen-pers@yandex.ru
Adgamov R.R. – junior researcher of the laboratory of ecology of pathogens, e-mail: bacter@yandex.ru
Surin A.K. – candidate of physical- mathematical sciences, researcher of the laboratory of protein physics, e-mail: alexey_surin@mail.ru
Psareva E.K. – junior researcher of the laboratory molecular bases of pathogenicity of bacteria, e-mail: katehok_84@mail.ru
Ermolaeva S.A. – doctor of medical sciences, professor, head of the laboratory of ecology of pathogens, e-mail: sveta@ermolaeva.msk.su
Timchenko N.F. – doctor of medical sciences, professor, head of the laboratory molecular bases of pathogenicity of bacteria, e-mail: ntimch@mail.ru
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