№ 4 / 2012 / 66-71

Features of clinico-biochemical and immunological parameters at patients with the arterial hypertensia, indigenous population of the North, comorbid with diseases of hepatobiliary system

Author: Nikolaev Yu.A.¹, Gevorgyan M.M.², Kozaruk T.V.³, Kuznetsova A.P.⁴, Polyakov V.Ya.⁵

Abstract

88 patients with arterial hypertension (AH) of II-III stage, I-II degrees and with hepatobiliary system (HBS) disorders have been surveyed in the clinic of FSBI “Scientific Center of Clinical and Experimental Medicine» of Siberian Branch of Russian Academy of Medical Science” (Novosibirsk). Among them, 67 people constantly live in moderate latitudes (Novosibirsk) and 21 people constantly live in the North (Republic Saha, Yakutia). All surveyed patients were in the age from 20 till 60 years. The features of clinico-biochemical and immunological parameters and their interrelation with the stage of disease at patients with AH and HBS in the North have been investigated. The comparison of values of immunological parameters has revealed the decrease in immune resistance at the patients living in the North in comparison with the patients — residents of middle latitudes. The interrelation of some biochemical and immunological parameters with stage of AH is established. These data testify to the contribution of change of organism pigmentary metabolism and immunological resistances to progressing disease in case of comorbide nosologies presence at the patients living in the North.

Key words

the North, arterial hypertension, diseases of hepatobiliary system, immunology, lipids

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About Authors (Correspondence):

Nikolaev Yu.A. – doctor of medical sciences, chief researcher, acting deputy director on scientific and medical work, head of the laboratory of somatic diseases pathogenesis of the department of medical-ecological investigations, e-mail: nicol@soramn.ru

Gevorgyan M.M. – candidate of medical sciences, head of the clinical-diagnostic department of the clinic, e-mail: gevorgyanmm@ngs.ru

Kozaruk T.V. – physician of the clinical-diagnostic department of the clinic

Kuznetsova A.P. – physician of the clinical-diagnostic department of the clinic, e-mail: kuzik86@mail.ru

Polyakov V.Ya. – candidate of medical sciences, senior researcher, e-mail: vpolyakov15@yandex.ru

Full Text

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Received: 10/02/2015