Forecasting of development of pneumonia at influenza А(Н1N1)/v at children
A research objective – identification of prognostic criteria of development of a pneumonia at influenza А(Н1N1)/v at children. Material and methods. 161 children were surveyed. The basic group of the investigated was made by 87 children with the pneumonia, associated with a influenza А(Н1N1)/v, comparison group – 74 children with an uncomplicated current of influenza А(Н1N1)/v. 87 indicators (clinical, laboratory, tool) defined at all patients were included into multifactorial regression model. Results and discussion. Independent criteria of development of a pneumonia at influenza А(Н1N1)/v are the increase of the content in serum of blood of the transformation growth factor-β1 (TGF β1), IL-10, IL-4 and parity change of metalloproteazy-9 to its specific fabric inhibitor.
About Authors (Correspondence):
Miromanova N.A. – candidate of medical sciences, associate professor, head of the chair of children infections