№ 4 / 2013 / 49-55

Neurotechnologies of audio-visual-vibrotactile stimulation in therapy of arterial hypertension in children and teenagers

Author: Aftanas L.I.¹, Yarosh S.V.², Nefedova J.V.³

Abstract

Therapeutic effects of the complex 2-weeks therapy of the three pathogenetically different forms of the arterial hypertension (AH) (mesenchymal dysplasia of connective tissue, n = 22; hypothalamic syndrome, n = 25; essential hypertension, n = 25) using pharmacotherapy (enalapril, propranolol) alone or combined with the audio-visual-vibrotactile stimulation (AVVS, 10 sessions of 30 min each during 14 days) in children and teenagers were studies. 24-hour arterial blood pressure measurements were made before and at the 14th day of the treatment. In comparison with the monotherapy by pharmacological preparations, the combined treatment (AVVS + pharmacotherapy) led to more efficient correction of abnormal day and night arterial blood pressure dynamics as well as to a two-fold decrease of intake doses of enalapril or propranolol. It has been suggested that AVVS combined with pharmacotherapy, make the overall treatment of arterial hypertension more efficient by improving mind-body interactions in hypertensive pathological states.

Key words

arterial hypertension,, audio-visual-vibrotactile stimulation, hypothalamic syndrome, children, mesenchymal dysplasia of connective tissue, combined therapy,, teenagers, propranolol, enalapril, essential hypertension

References

1. Agadzhanyan N.A.. Notova S.N. Stress, physiological and ecological aspects of adaptation, correction ways. Orenburg: OSU, 2009. 274 p. (In Russian)

2. Pat. 2314132 RF. Method of drug-free correction of human psycho-emotional, neuro-hormonal and immune statuses. Aftanas L.I., Baiduzha V.P., Grishchuk I.V. etc.; published in 10.01.2012. (In Russian)

3. Pat. 2466677 RF. Method of drug-free correction and/or optimization of human emotional neuro-vegetative and neuro-cognitive statuses. Aftanas L.I., Novopashina A.V.; published in 20.11 2012. (In Russian)

4. Aftanas L.I., Bokhan N.A., Mandel A.I. etc. Effectiveness of audio-visual-vibrato-tactile stimulation on the correction of psycho-vegetative disorders at women alcoholism at the stage of remission forming. Sibirsky vestnik psikhiatrii i narkologii. 2012. 69. (4). 47–52. (In Russian)

5. Kobalova Zh.D.,,Kotovskaya Yu.V. Arterial hypertension: ways of diagnostics and treatment. М., 2007. 432 p. (In Russian)

6. Leonteva I.V., Agapitov L.I. Method of 24-hours monitoring of blood pressure in diagnostics of arterial hypertension in children. Ros. vestn. perinatol. pediatrii. 2000. (2). 32–38. (In Russian)

7. Handbook on rehabilitation of people under stress load. Ed. V.I. Pokrovsky. М.: Meditsyna, 2004. 400 p. (In Russian)

8. Shlyakhto E.V. Pathogenesis of hypertension (essential hypertension). Handbook on arterial hypertension. Ed. Е.I. Chazov, I.Е. Chazova. М. Media Medika, 2005. 41–60. (In Russian)

9. Huang T., Charyton Ch. A comprehensive review of the psychological effects of brainwave entrainment // Altern. Ther. Health Med. 2008. 14. (5). 38–49.

10. Jennings J.R., Heim A.F. From brain to behavior: Hypertension's modulation of cognition and affect // Int. J. Hypertens. 2012. 2012. ID 701385.

11. Kumano H., Horie H., Kuboki T. et al. EEG-driven photic stimulation effect on plasma cortisol and beta-endorphin // Appl. Psychophysiol. Biofeedback. 1997. 22. (3). 193–208.

12. Le Scouarnec R.P., Poirier R.M., Owens J.E. et al. Use of binaural beat tapes for treatment of anxiety: a pilot study of tape preference and outcomes // Altern. Ther. Health. Med. 2001. 7. (1). 58–63.

13. Oparil S., Zaman A., Calhoun D. Pathogenesis of hypertension // Ann. Intern. Med. 2003. 139. (9). 761–776.

14. Ossebaard H.C. Stress reduction by technology? An experimental study into the effects of brainmachines on burnout and state anxiety // Appl. Psychophysiol. Biofeedback. 2000. 25. (2). 93–101.

15. Salansky N., Fedotchev A., Bondar A. Responses of the nervous system to low frequency stimulation and EEG rhythms: clinical implications // Neurosci. Biobehav. Rev. 1998. 22. 395–409.

16. Siever D., Berg K. Helping the heart with audio-visual entrainment // Appl. Psychophysiol. Biofeedback. 2002. 27. (4). 313.

17. Teplan M., Krakovská A., Stolc S. Direct effects of audio-visual stimulation on EEG // Comput. Methods Programs Biomed. 2011. 102. (1). 17–24.

18. Thayer J.F., Ahs F., Fredrikson M. et al. A meta-analysis of heart rate variability and neuroimaging studies: implications for heart rate variability as a marker of stress and health // Neurosci. Biobehav. Rev. 2012. 36. (2). 747–756.

About Authors (Correspondence):

Aftanas L.I. – doctor of medical sciences, professor, academician of RAMS, vice president RAMS, director, e-mail: l.aftanas@physiol.ru

Yarosh S.V. – researcher, e-mail: yarosh@physiol.ru

Nefedova J.V. – doctor of medical sciences, assictant professor, depvice-dean of feculty of general medicine, e-mail: nefedova_doc@mail.ru

Full Text

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Received: 02/02/2015