№ 4 / 2013 / 56-64

Ultrasound assessment and prognostic importance of indicators of cardiopulmonary hemodynamics in hepatic cirrhosis

Author: Kalacheva T.P.¹, Chernyavskaya G.M.², Beloborodova E.I.³

Abstract

The research objective is to conduct an integrated study of structural and functional indicators of cardiopulmonary hemodynamics by Doppler echocardiography, as well as to assess presence and intensity of pulmonary arterial hypertension in patients with hepatic cirrhosis of various severity and to determine its influence on the course and forecast of the underlying disease. Results. It was established that changes in the structural and functional cardiac indicators in hepatic cirrhosis depend on the stage of portal hypertension compensation and are accompanied by alteration of intracardiac hemodynamics parameters. Pulmonary arterial hypertension was detected in 11.1 % of patients with hepatic cirrhosis; it was moderate and occurred in patients with the terminal stage of the disease (class C according to Child – Pugh) in contrast to the early stage of cirrhosis (21.4 % as opposed to 6.3 %, thus, р < 0.05). Conclusion. The results of 2-year examination showed that presence of pulmonary arterial hypertension makes the clinical course of hepatic cirrhosis more severe, correlates with a decrease in life expectancy of cirrhotic patients and is a factor of unfavourable clinical forecast for this group of patients.

Key words

pulmonary arterial hypertension, cardiopulmonary hemodynamics, portal hypertension, hepatic cirrhosis

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About Authors (Correspondence):

Kalacheva T.P. – candidate of medical sciences, assistant of the chair of skill improvement and professional retraining faculty, e-mail: talyana-kalachvova@y;mdex.ru

Chernyavskaya G.M. – doctor of medical sciences, professor of the chair of skill improvement and professional retraining faculty, e-mail: chernyavskayag@mail.ru

Beloborodova E.I. – doctor of medical sciences, professor of the chair of skill improvement and professional retraining faculty, e-mail: belobekaterina@yandcx.ru

Full Text

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Received: 02/02/2015