The role of orbital eye blood flow changes in the development of the optic neuroretinopathy in children with primary congenital glaucoma

Objective: To study the pathogenetic significance of orbital eye blood flow changes in the development of glaucomatous neuroretinopathy in children with congenital glaucoma. Material and methods: A comparative analysis of electrophysiological and dopplerographic parameters of 42 children with congenital glaucoma and 20 control children has been carried out. Results and discussion: The index of regional ocular blood flow is down-regulated in children with congenital glaucoma. The positive correlation between the regional ocular blood flow deficiency and the retinal functional activity has been revealed.

1. Avetisov A.S., Khvatova А.V., Angelov V.О. Selective Data of Prevalence of Children Pathology of the Eye // Vestn. ophtalmologii. 1983. 2.  32-37. (in Russian)

2. Ahrorova Z.D., Gafurova L.B. Social-biological Aspects of Hydrophtalma // VII Сongress of Ophtalmologists. Moskva, 2000. 328-329. (in Russian)

3. Yegorova I.V. Functional Methods of Investigation in Glaucoma Diagnosis // Glaucoma. 2003. 2. 39-45. (in Russian)

4. Yegorova I.V., Shamshinova А.М., Yerichev V.P.  Psychophysical and Electrophysiological Methods of Investigation in Glaucoma Diagnosis // Clinical Vision  Physiology. Moskva, 2002. 400-411. (in Russian)

5. Pospelov V.I. Reasons of Children Blindness // All-Russian Congress of Children Ophtalmologists.  Moskva, 1996. 13-15. (in Russian)

6. Saidasheva A.I., Somov Е.Е., Fomina N.V. Congenital Glaucoma //  Selected Lectures on Innatal Ophtalmology. SPb., 2006. 105-126. (in Russian)

7. Sidorenko E.I. Children Glaucoma [Electronic Resource]// RMG. Klinicheskaya oftalmologiya. 2003. 4(2). Conditions of access: http://www.rmj.ru/numbers_348.htm. №  reg. FS 77-41718. (in Russian)

8. Fenkova O.G., Fursova А.Zh., Gusarevich О.G. Clinico-morphological and Functional Criteria of Evaluation of Congenital Glaucoma Degree // RMG. Klinicheskaya oftalmologiya. 2011. 12(2). 56-58. (in Russian)

9. Khvatova А.V., Teplinskaya L.E., Yakovlev А.А.  Congenital Glaucoma: Modern View of Pathogenezis and Treatment // Optic Functions and Their Correction for Children: Manual for Physicians. Moskva, 2005. 319-344. (in Russian)

10. Shamshinova A.M., Каzaryan А.А. Оptical Neuropation of Glaucomic Genezis // Electroretinography in Ophtalmology. Moskva, 2009. 242-259. (in Russian)

11. Bui B.V., Armitage J.A. Extraction and mode­ling of oscillatory potentials // Doc. Ophthalmol. 2002. 104. (1). 17–36.

12. Kriss A., Russel-Eggitt I. Electrophysiological assessment of visual pathway function in infants // Eye. 1992. 6. 145–153.

13. Neufeld M.H., Liu B. Glaucomatous optic neuropathy, when glia misbehave // Neuroscientist. 2003. 9. 485–495.

Gusarevich O.G. – doctor of medical sciences, professor of the chair of ophthalmology, ophthalmologist, e-mail: olga.gusarevich@gmail.com