Postoperative cognitive dysfunctions in cardiac surgery: pathogenesis, morphological and functional correlates, diagnostics
Abstract
The paper reviews the current understanding of the pathogenetic mechanisms and morphological and functional correlates of postoperative cognitive dysfunction (POCD) in cardiac surgery patients, analyzes the advantages and disadvantages of different approaches to their diagnostics. An increase of the relative contribution of general surgical factors and the patient’s risk factors to the POCD pathogenesis is demonstrated. Basing on the analysis of POCD diagnostics methods the main principles which should be followed have been suggested and the actuality of «right-hemispheric» tests including into test batteries and analysis of the indexes reflecting the frontal lobe function has been shown.
Key words
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Levin E.A. – candidate of biological sciences, senior researcher of the group of neuroreanimatology, e-mail: e.a.levin@gmail.com
Postnov V.G. – doctor of medical sciences, leading researcher, head of the group of neuroreanimatology, e-mail: v_postnov@nricp.ru
Vasyatkina A.G. – candidate of medical sciences, researcher of the group of neuroreanimatology, e-mail: a_vasyatkina@nricp.ru
Zhukova O.V. – junior researcher of the group of neuroreanimatology, e-mail: o_zhukova@nricp.ru
