№ 4 / 2013 / 107-114

Adipose tissue hormones and age obesity in women

Author: Selyatitskaya V.G.¹, Galanova Zh.M.², Poteryaeva E.L.³, Kuzminova O.I.⁴, Pinkhasov B.B.⁵, Mitrofanov I.M.⁶

Abstract

The aim of research was to determine in healthy women the relationship of anthropometric and hormonal-biochemical parameters of organism in age aspect. In 122 women aged 21 to 74 years a growth, body mass, waist and hips circumferences, thick fat folds, relative fat content were identified; in serum concentrations of hormones – leptin, adiponectin, immunoreactive insulin, cortisol were measured; the values of carbohydrate and fat metabolism were determined. The relationship of studied parameters in the women groups of first (group 1) and second (group 2) periods of mature both with middle (group 3) ages were described by rank correlation analysis. The most pronounced increase in anthropometric variables and the concentration of triglycerides in the blood serum were observed in group 2 women with respect to group 1. The leptin concentrations in the blood serum was increased in group 2 relative to group 1 and in group 3 relative to group 2, but for all that the adiponectin concentrations in the blood serum was not changed. The correlation analysis of anthropometric parameters calculated values measures such as body mass index and waist to hip circumference ratio with the values of hormonal and biochemical parameters showed that the number of statistically significant correlations greatly higher in the group 2 (n = 10) than in 1 (n = 3) or 3 (n = 1) women age groups. The correlations structure was differed too.

Key words

adiponectin, age groups, women, body mass index, leptin, waist to hip circumferences ratio, carbohydrate and fat metabolism

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About Authors (Correspondence):

Selyatitskaya V.G. – doctor of biological sciences, professor, head of the laboratory of endocrinology, e-mail: ccem@soramn.ru

Galanova Zh.M. – postgraduate student of the chair of emergency therapy with endocrinology and occupational pathology of the faculty of training and retraining of physicians, e-mail: sovetmedin@yandex.ru

Poteryaeva E.L. – doctor of medical sciences, professor, head of the chair of emergency therapy with endocrinology and occupational pathology of the faculty of training and retraining of physicians, e-mail: sovetmedin@yandex.ru

Kuz’minova O.I. – candidate of medical sciences, senior researcher of the laboratory of endocrinology

Pinkhasov B.B. – candidate of medical sciences, senior researcher of the laboratory of endocrinology

Mitrofanov I.M. – doctor of medical sciences, leading researcher of the laboratory of somatic diseases pathogenesis

Full Text

15-4-2013.pdf

Received: 02/02/2015