The study of the response of rat’s ocular blood flow to the administration of vascular endothelial growth factor by ultrasonic Doppler methods
The ocular blood flow in rat’s eyes in vivo has been studied with the use of modern ultrasonic methods and a scheme of the flow has been presented. Marked similarities in the structure of ocular blood vessels in rats and humans are noted. The influence of intravitreal administration of the vascular endothelial growth factor on ocular blood flow has been studied by means of an experimental model of ocular neovascularization. The initial brief increase in the ocular blood flow as a reaction to the development of ischemia was followed by the normalization or reduction of the parameters of the blood flow.
About Authors (Correspondence):
Neroev V.V. – doctor of medical sciences, professor, head of retinal pathology department
Kiseleva T.N. – doctor of medical sciences, professor, head of ultrasound department
Ryabina M.V. – candidate of medical sciences, senior researcher of retinal pathology department
Okhotsimskaya T.D. – candidate of medical sciences, physician of retinal pathology department, e-mail: firstname.lastname@example.org
Zolotych O.V. – candidate of medical sciences, physician of retinal pathology department