№ 1 / 2015 / 48-54

Effect of cataract surgery on intraocular pressure in patients with pseudoexfoliation syndrome

Author: Malyugin B.E.¹, Agafonova V.V.², Frankovska-Gerlak M.Z.³, Chubar V.S.⁴, Khaludorova N.B.⁵

Abstract

MATERIAL AND METHODS. The study was conducted on 258 eyes of 138 patients with cataract and PEX. All patients with cataract and PEX were divided into three study groups: Group 1 with normal IOP before surgery; Group 2 with borderline IOP before surgery (IOP 21–27 mm Hg), Group 3 was comprised of patients with primary open angle glaucoma treated solely with anti-hypertensive drugs. Patients were followed up for 6 months. RESULTS. Six months after cataract surgery the most pronounced hypotensive effect was observed in Group 2 and averaged 8.95 mm Hg (Δ IOP 39.85 %) (p < 0.05). In Group 1 and Group 3 the decrease in IOP was 5.16 (Δ IOP 6.9 %) and 5.5 (Δ IOP 28.67 %) respectively. CONCLUSION. The strong tendency to reduction of IOP post- surgery in all groups was revealed in patients with cataract and PEX six months after surgery. The most pronounced hypotensive effect was observed in patients with cataract and PEX and borderline IOP prior to surgery, Δ average IOP was 39.85 % (p < 0.05).

Key words

intraocular pressure, pseudoexfoliation syndrome, Phacoemulsification

References

1. Agafonova V., Frankovska-Gierlak M., Chubar V., Brizgak P. Effect of cataract surgery on in traocular pressure in patients with openangle glaucoma and pseudoexfoliation syndrome in early postoperative period // Prakticheskaya meditsina. 2013. (1–3). 23–27. (in Russian)

2. Krol D.S. Pseudoexfoliation Syndrome and Exfoliative glaucoma: abstract of thesis ... doctor of medical sciences. Kuibyshev, 1969. (in Russian)

3. Malyugin B.E. Medical and technological system of surgical rehabilitation of cataract patients on the basis of ultrasound phacoemulsification with intraocular lens implantation: abstract of thesis ... doctor of medical sciences. Moscow, 2002. (in Russian)

4. Nesterov A.P. Glaucoma. Moscow: MIA, 2008. 360 p. (in Russian)

5. Racine O.G., Savchenko A.V., Litvinenko O.A., Zhivoglazova E.P. Hypotensive effect of cataract phacoemulsification in patients with open angle glaucoma // Tavricheskiy medico-biologicheskiy vestnik. 2012. (2). 191–194. (in Russian)

6. Вuratto L. Хирургия катаракты – переход от экстракапсулярной экстракции катаракты к факоэмульсификации. М.: Fabiano Editore, 1999. 474 с.

7. Fogagnolo P., Centofanti M., Figus M. Short-term changes in intraocular pressure after phacoemulsification in glaucoma patients // Ophthalmologica. 2012. 228. (3). 154–158.

8. Guan H., Mick A., Porco T., Dolan B.J. Preoperative factors associated with IOP reduction after cataract surgery // Optom. Vis. Sci. 2013. 90. (2). 179–184.

9. Kim M., Park K.H., Kim T.W., Kim D.M. Anterior chamber configuration changes after cataract surgery in eyes with glaucoma // Korean J. Ophthalmol. 2012. 26. (2). 97–103.

10. Mansberger S.L., Gordon M.O., Jampel H. et al. Ocular Hypertension Treatment Study Group. Reduction in intraocular pressure after cataract extraction: the Ocular Hypertension Treatment Study // Ophthalmology. 2012. 119. (9). 1826–1831.

11. Mansberger S.L., Gordon M.O., Jampel H. et al. Phacoemulsification and intraocular lens implantation in eyes with open-angle glaucoma // Acta Ophthalmol. Scand. 2001. 79. (3). 313–316.

12. Poley B.J., Lindstrom R.L., Samuelson T.W., Schulze R.Jr. Intraocular pressure reduction after phacoemulsification with intraocular lens implantation in glaucomatous and nonglaucomatous eyes: evaluation of a causal relationship between the natural lens and open-angle glaucoma // J. Cataract Refract. Surg. 2009. 35. (11). 1946–1951.

13. Rao A. Diurnal curve after phacoemulsification in patients with pseudoexfoliation syndrome and cataract // Semin. Ophthalmol. 2012. 27. (2). 1–5.

14. Sarda V., Rohart C., Fajnkuchen F. et al. Pseudoexfoliation syndrome and phacoemulsification: comparative study with a control population // J. Fr. Ophtalmol. 2010. 33. (5). 319–326.

15. Shingleton B.J., Heltzer J., O’Donoghue M.W. Outcomes of phacoemulsification in patients with and without pseudoexfoliation syndrome // J. Cataract Refract. Surg. 2003. 29. (6). 1080–1086.

16. Shingleton B.J., Nguyen B.K., Eagan E.F. et al. Outcomes of phacoemulsification in fellow eyes of patients with unilateral pseudoexfoliation: single-surgeon series // J. Cataract Refract. Surg. 2008. 34. (2). 274–279.

17. Shingleton B.J., Laul A., Nagao K. et al. Effect of phacoemulsification on intraocular pressure in eyes with pseudoexfoliation: single-surgeon series // J. Cataract Refract. Surg. 2008. 34. (11). 1834–1841.

18. Sufi A.R., Singh T., Mufti A.A., Rather M.H. Outcome of phacoemulsification in patients with and without pseudoexfoliation syndrome in Kashmir // BMC Ophthalmol. 2012. 6. 12–13.

About Authors (Correspondence):

Malyugin B.E. – doctor of medical sciences, professor, deputy general director for science

Agafonova V.V. – doctor of medical sciences

Frankovska-Gerlyak M.Z. – candidate of medical sciences, ophthalmologist, researcher of department for surgery and intraocular lens correction

Chubar V.S. – ophthalmologist, postgraduate student of department for surgery and intraocular lens correction, e-mail: tius87@mail.ru

Khaludorova N.B. – ophthalmologist, postgraduate student of department for surgery and intraocular lens correction

Full Text

9-1-2015.pdf

Received: 17/02/2015