№ 3 / 2015 / 65-73

Intraoperative intra-aortic balloon pump and levosimendan use in cardiosurgery in high-risk patients

Author: Lomivorotov V.V.¹, Boboshko V.A.², Boboshko A.V.³, Chernyavskiy A.M.⁴, Nikolaev D.A.⁵, Kornilov I.A.⁶, Shilova A.N.⁷, Lomivorotov V.N.⁸

Author Affiliations

Abstract

Aims. The comparative analysis of using intraoperative intra-aortic balloon pump (IABP) and levosimendan in high risk cardiac patients (LVEF<35 %) operated under CPB has been carried out. Methods. The intra-aortic balloon pump was started immediately after anesthesia induction in 24 patients; another 24 had a levosimendan infusion starting after anesthesia induction with the initial bolus of 12 mg/kg for 10 min, followed by 0,1 mg/kg/min for 24 h. Hemodynamics, troponin I levels, postoperative complications were evaluated. Results & conclusion. It was shown that the use of intraoperative IABP and levosimendan are effective ways of circulatory support. In addition, levosimendan has the more pronounced cardioprotective effect, and levosimendan use reduces the length of intensive care unit stay and hospitalization.

Key words

coronary artery bypass grafting, intra-aortic balloon pump, cardiopulmonary bypass, levosimendan, heart failure

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About Authors (Correspondence):

Lomivorotov V.V. – doctor of medical sciences, professor, director of the center of anesthesiology and intensive care, deputy director for science, e-mail: vvlom@mail.ru

Boboshko V.A. – candidate of medical sciences, anesthesiologist, e-mail: vaboboshko@gmail.com

Boboshko A.V. – candidate of medical sciences, cardiovascular surgeon

Chernyavsky A.M. – honored scientist of the RF, doctor of medical sciences, professor, head of the center of surgery of aorta, coronary and peripheral arteries

Nikolaev D.A. – postgraduate student, junior researcher, anesthesiologist, e-mail: nikolaev.d.md@gmail.com

Kornilov I.A. – candidate of medical sciences, anesthesiologist, head of the

Shilova A.N. – doctor of medical sciences, doctor of clinical and laboratory diagnostics, head of the group of clinical and biochemical researches

Lomivorotov V.N. – doctor of medical sciences, professor, deputy director

Full Text

10-3-2015.pdf

Received: 01/07/2015

Intraoperative intra-aortic balloon pump and levosimendan use in cardiosurgery in high-risk patients

Abstract

Key words

Meco M., Gramegna G., Yassini A. et al. Mortality and morbidity from intra-aortic balloon pumps. Risk analysis // J. Cardiovasc. Surg. (Torino). 2002. 43. (1). 17–23.

Full Text