Studies of the rates of hemodynamics in the eye blood vessels and the eye-sockets in patients chronically exposed to radiation
Author Affiliations1Urals Scientific and Practical Center for Radiation Medicine, 454076, Chelyabinsk, Vorovskogo str., 68a
Abstract
The characteristics of the hemodynamics of the eye and the eye-socket vessels in persons with a history of a long-term low-intensity radiation exposure were studied. The main group consisted of 25 patients with high exposure doses to soft tissues (based on the TRDS-2000 data, the exposure doses exceeded 0.4 Gr and the medium doses amounted to 0.3 Gr. The control group included 27 patients with low exposure doses (from 0 to 0.02 Gr), the medium dose was equal to 0.01 Gr. The blood flow characteristics were assessed in the ophthalmic artery (OA), the central artery of the retina (CAR), and in the rear short ciliary arteries (RSCA). In order to evaluate the hemodynamics in the eye vessels and in the eye-socket, the ultrasonic dopplerography with color Doppler imaging of orbital vessels was used which allowed to estimate the blood circulation time in the vessels of the eyebulb and the eye-socket, and the blood supply to them, and also, to estimate the pulsation rate. According to the data on color Doppler ultrasonic imaging of the eye and orbit in persons chronically exposed to radiation during the late period after the beginning of the exposure decreased blood velocity characteristics were noted (Vmax in the ophthalmic artery, Vmin in the rear short ciliary arteries) and an increased index of the peripheral resistance (RI) in the last ones. The results obtained testify to the regional hemodynamic abnormalities in cases of chronic radiation exposures. Based on the data of the clinical and instrumental examinations, prognostic criteria for the development of particular forms of eye pathology in persons chronically exposed to radiation have been developed.
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About Authors (Correspondence):
Mikryukova L.D. – candidate of medical sciences, researcher of epidemiological, e-mail: mik@urcrm.ru
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