Activating effect of antler hematogen upon the reactions of hemostasis system
Author Affiliations1Altai State Medical University of Minzdrav of Russia, 656038, Barnaul, Lenin str., 40
2Altai State Medical University of Minzdrav of Russia, 656038, Barnaul, Lenin str., 40; Scientific Research Institute of Physiology and Basic Medicine, 630117, Novosibirsk, Timakov str., 4
3Altai State Medical University of Minzdrav of Russia, 656038, Barnaul, Lenin str., 40
4Altai State Medical University of Minzdrav of Russia, 656038, Barnaul, Lenin str., 40; Scientific Research Institute of Physiology and Basic Medicine, 630117, Novosibirsk, Timakov str., 4
Abstract
The objective of the present research is to assess reactions of hemostatic system after preliminary administration of antler hematogen in courses of different duration. Methods and material. 50 adult male Wistar rats were used in the present work. In the course of the experiment three groups of animals were taking 6 ml of antler hematogen per day for 7, 14 and 30 days respectively. Results and their discussion. It was experimentally established that the 7-day administration of antler hematogen had different effects upon plasma hemostasis and increased anticoagulant activity of blood plasma. After 30 days of administration of the preparation an increase in platelet aggregation, hypercoagulation at all stages of plasma hemostasis, an increase in anticoagulant and fibrinolytic activity of plasma were noted.
Key words
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About Authors (Correspondence):
Blazhko A.A. – lecturer of the chair for normal physiology, е-mail: blazhko_1990@mail.ru
Shakhmatov I.I. – doctor of medical sciences, head of the chair for normal physiology, senior researcher, е-mail: iish59@yandex.ru
Moskalenko S.V. – student, sunrisemsv@gmail.com
Lycheva N.A. – candidate of medical sciences, junior researcher, е-mail: kuzminan_86@mail.ru