Pharmacological modification of coronary stents
Abstract
The article presents data on the creation of innovative drug covering for coronary stents, which are used in the treatment of acute myocardial infarction. Objective: to determine kinetic parameters of polyarginine complex extraction from the coronary stents polymer matrix. Material and Methods: coronary stent, polymer matrix polylactide-glycolide, arginine polypeptide complex. Results: the new drug covering for a coronary stent which possesses delayed polyarginine release from polymeric matrix is created.
Key words
ReferencesMarinkin I.O. – doctor of medical sciences, professor, rector
Madonov P.G. – doctor of medical sciences, professor, head of the chair for pharmacology, clinical pharmacology and evidentiary medicine, e-mail: madonov@scpb.ru
Mishenina S.V. – candidate of medical sciences, associated professor of the chair for pharmacology, clinical pharmacology and evidentiary medicine
Dubrovin A.V. – researcher of central research laboratory
Miroshnikov P.N. – researcher of central research laboratory
Yershov K.I. – candidate of medical sciences, assistant of the chair for pharmacology, clinical pharmacology and evidentiary medicine
Pozdnyakova S.V. – doctor of medical sciences, professor of the chair for pharmacology, clinical pharmacology and evidentiary medicine
