EXPERIMENTAL STUDY OF IMMOBILIZED SUBTILYZINES INFLUENCE ON REPRODUCTIVE TOXICITY. II. POSTNATAL PERIOD
Author Affiliations1Goldberg Research Institute of Pharmacology and Regenerative Medicine
2Goldberg Research Institute of Pharmacology and Regenerative Medicine
3Goldberg Research Institute of Pharmacology and Regenerative Medicine
4Novosibirsk State Medical University of Minzdrav of Russia
5Novosibirsk State Medical University of Minzdrav of Russia, 630091, Novosibirsk, Krasny av., 52
6Novosibirsk State Medical University of Minzdrav of Russia
Abstract
The introduction of immobilized subtilisins causes a number of toxic effects in the postnatal period of development. Reduced viability, slower physical development, speed of formation of sensory-motor reflexes, decreased ability to learn, delay of unconditioned reflexes were detected in the offspring of rats that received immobilized subtilisins during pregnancy.
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About Authors (Correspondence):
Madonov P.G. – doctor of medical sciences, professor, head of department of for pharmacology, clinical pharmacology and evidentiary medicine, e-mail: madonov@scpb.ru
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