The Siberian Scientific Medical Journal
№ 1 / 2018 / 69-76
DOI 10.15372/SSMJ20180111


Author Affiliations


We have summarized the results of national and foreign studies dealing with the questions of proliferative vitreoretinopathy (PVR) pathogenesis, treatment and prophylaxis. Rhegmatogenous retinal detachment (RRD) is one of the most severe ocular diseases that very often leads to the significant reduction of visual functions, disability and if untreated to irreversible blindness. Many studies have proved that the postoperative functional result depends on a number of factors including the severity of proliferative retinopathy. PVR is a term that is inseparably linked with the description of a wide spectrum of vitreoretinal pathology accompanied by the processes of pathological membrane formation on the retinal surface and in the vitreous body, leading eventually to the irreversible and inoperable changes. Currently surgical method of PVR treatment is considered the most effective. Surgical technique in PVR depends on the stage of the disease. PVR diagnosis in the early stages is problematic, and the disease is diagnosed when discovering the epi- and/or subretinal proliferative membranes been already formed. Currently there are no criteria for assessing the possibility of PVR development and progression followed surgical treatment. Despite modern advances in the study of PVR etiology and pathogenesis, the improvement of surgical techniques of treating RRD, the problem of proliferative disease prevention and treatment remains topical and requires further treatment.

Key words

ophthalmology, proliferative vitreoretinopathy, rhegmatogenous retinal detachment
About Authors (Correspondence):

Fabrikantov O.L. – doctor of medical sciences, director, head of ophthalmological department, email:

Full Text

Received: 26/02/2018
Accepted: 26/02/2018