The Siberian Scientific Medical Journal
 
 
№ 6 / 2018 / 19-23
DOI 10.15372/SSMJ20180603

ON THE INTERACTION OF LIQUID FLOW IN THE SYSTEM «BLOOD CAPILLARY – TISSUE – LYMPHATIC CAPILLARY»

Author Affiliations

Abstract

The article deals with the interaction of fluid flow in the «blood capillary – tissue – lymphatic capillary» system. On the one hand, the mutual influence of the components involved in the system is an important basis for maintaining homeostasis from the point of view of physiologically occurring processes, and changes in their structural and functional properties can be a triggering factor for impaired fluid balance, the appearance and development of a number of pathological processes, syndromes and diseases. The paper presents a mathematical model of metabolic processes that occur at the microcirculatory level and include the following interrelated processes: blood flow in the capillaries, fluid movement in the interstitium, metabolism between interstitial fluid and tissue cells, drainage into lymphatic capillaries. An approach is used to take into account the mutual influence of blood flow in the blood capillary and interstitial fluid in the tissue. The analysis of the solution results is carried out, the effect of various microcirculation parameters on the intensity of metabolic processes is investigated, and the most significant parameters are identified.

Key words

microcirculation, mathematical modeling, lymphatic drainage, interstitium
References
About Authors (Correspondence):

Shvab I.V. – candidate of technical sciences, researcher, docent of the chair for mathematics, e-mail: Schwab_irina@mail.ru

Full Text

Received: 18/12/2018
Accepted: 18/12/2018