The Siberian Scientific Medical Journal
 
 
№ 6 / 2014 / 82-87

Influence of bronchial asthma debut on its course clinical functional peculiarities

Author Affiliations

Abstract

452 patients with bronchial asthma were subjected to clinical-functional and immunological check-up. All of them were divided into two groups: the first group consists of 286 patients with the disease first manifestation after the age of 40 year i.e. people with late asthma, the second group consists of 166 patients with bronchial asthma debut before the age of 40. Our investigation showed that the late asthma has severer instable course and often atypical clinical manifestation. Eosinophyli-neutrophilic inflammation development is a specific marker of late asthma. Diagnostic and prognostic markers of late asthma were developed. The treatment programs were elaborated in consideration of the clinical functional and immunological peculiarities.

Key words

bronchoalveolar lavage, bronchoscopy, late asthma
References
About Authors (Correspondence):

Kudelya L.M. – doctor of medical sciences, professor, honored physician of the RF, head of pulmonological department, professor of the internal diseases chair, chief pulmonologist of the Novosibirsk region, e-mail: oxy80@mail.ru

Sidorova L.D. – doctor of medical sciences, professor, academician of RAS, honored scientist, professor of the internal diseases chair

Mozhina L.N. – candidate of medical sciences, associate professor of the internal diseases chair

Tikhomirova E.G. – candidate of medical sciences, assistant of internal diseases chair

Manzhileeva T.V. – candidate of medical sciences, assistant of internal diseases chair

Full Text

Received: 12/02/2015