Bifidobacterium species range and microbial landscape of the large intestine in children with functional disorders of the digestive system
Author Affiliations1Scientific Center of Family Health and Human Reproduction Problems of SB RAMS, 664025, Irkutsk, Timiryazev str., 16
2Scientific Center of Family Health and Human Reproduction Problems of SB RAMS, 664025, Irkutsk, Timiryazev str., 16
3Scientific Center of Family Health and Human Reproduction Problems of SB RAMS, 664025, Irkutsk, Timiryazev str., 16
4Scientific Center of Family Health and Human Reproduction Problems of SB RAMS, 664025, Irkutsk, Timiryazev str., 16
5Scientific Center of Family Health and Human Reproduction Problems of SB RAMS, 664025, Irkutsk, Timiryazev str., 16
6Scientific Center of Family Health and Human Reproduction Problems of SB RAMS, 664025, Irkutsk, Timiryazev str., 16
7Scientific Center of Family Health and Human Reproduction Problems of SB RAMS, 664025, Irkutsk, Timiryazev str., 16
8Scientific Center of Family Health and Human Reproduction Problems of SB RAMS, 664025, Irkutsk, Timiryazev str., 16
Abstract
The main objective of this work was to study bifidobacteria species range by means of method of polymerase chain reaction in different age children with functional gastro-intestinal tract disorders. General intestine microecological characteristics in children were studied too. Disbiotic changes in the intestinal biotope were accompanied by bifidobacteria deficiency and opportunistic microorganisms selection. Reduction of B.longum and B.catenulatum populations, the appearance of bifidobacteria rare species B. dentium и B. angulatum were shown. Decrease in bifidobacteria species diversity in children with functional gastro-intestinal tract disorders indicated instability in gut microecosystem. The study of bifidobacterial profiles in different pathologies will contribute to the early diagnosis and diseases treatment.
Key words
References
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About Authors (Correspondence):
Nemchenko U.M. – junior researcher of the laboratory for microecology, e-mail: lav0467@mail.ru
Popkova S.M. – doctor of biological sciences, head of the laboratory for microecology, e-mail: smpopkova@gmail.com
Rakova E.B. – candidate of biological sciences, researcher of the laboratory for microecology, e-mail: lenova_@mail.ru
Rychkova L.V. – doctor of medical sciences, head of department of pediatrics
Serdyuk L.V. – candidate of biological sciences, researcher of the laboratory for microecology, e-mail: radugarose@yandex.ru
Ivanova E.I. – junior researcher of the laboratory for microecology, e-mail: ivanova.iem@gmail.com
Savel’kaeva M.V. – gastroenterologist, doctor of highest category
Dzhioev Yu.P. – candidate of biological sciences, senior researcher, e-mail: alanir07@mail.ru
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