Problems of laboratory based prevention of vascular accidents using various commercial lupus anticoagulant detection reagent kits
Author Affiliations1Omsk State Medical University, 644099, Omsk, Lenin str., 12
2Omsk State Medical University, 644099, Omsk, Lenin str., 12
3Omsk State Medical University, 644099, Omsk, Lenin str., 12
4Omsk State Medical University, 644099, Omsk, Lenin str., 12
Abstract
Standardization of lupus anticoagulant detection methods is a difficult problem. The International Society on Thrombosis and Hemostasis (ISTH) issued the «Update of the guidelines for lupus anticoagulant detection» in 2009 to solve this task. The characteristics of Russian-manufactured reagent kits and descriptions of study protocols for lupus anticoagulant detection have been analyzed for the purpose of compliance with the ISTH Guidelines. It has been revealed that reagents of only 2 (among 8) manufacturers matched with the ISTH Guidelines. The significant deviations from this document have been revealed in manuals from other reagent kits manufacturers.
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References
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About Authors (Correspondence):
Indutny A.V. – doctor of medical sciences, associate professor, head of the departmentof clinical laboratory diagnostics, leading researcher of central research laboratory, e-mail: anton@indutny.com
Vavilova T.V. – doctor of medical sciences, professor, head of the department of clinical laboratory diagnostics and genetics, leading researcher of central research laboratory, e-mail: cnil.osma@gmail.com
Novikov D.G. – candidate of medical sciences, head of the central research laboratory, e-mail: novikov.dm.omsk@gmail.com
Barsukov А.А. – internship doctor of department of clinical laboratory for diagnostics, e-mail: a.barsukov.omsk@gmail.com
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