Differentiated approach to the choice of the extent of surgery for patients with invasive cervical cancer
Abstract
Cervical cancer is the 4th most common cancer in women worldwide. Currently, novel approaches to treatment of cervical cancer, namely organ-preserving and function-sparing surgeries, aimed to improve life quality of patients and their medical and social rehabilitation are being developed and actively implemented. We present a literature review using data from our studies on the feasibility of a differentiated approach to the choice of tactics in treatment of patients with invasive cervical cancer.
Key words
ReferencesAbu-Rustum N.R., Neubauer N., Sonoda Y. et al. Surgical and pathologic outcomes of fertility-sparing radical abdominal trachelectomy for FIGO stage IB1 cervical cancer // Gynecol. Oncol. 2008. 111. (2). 261-264.
ACOG Practice Bulletin, Clinical management guidelines for obstetrician-gynecologists. No. 35, May 2002: Diagnosis and treatment of cervical carcinomas // Obstet. Gynecol. 2002. 99. 855–866.
Altgassen C., Hertel H. Multicenter validacion study of the sentinentel lymph node concept in cervical cancer: AGO Study Group // J. Clin. Oncol. 2008. 26. 2943-2951.
Averette H.E., Nguyen H.N., Donato D.M. et al. Radical hysterectomy for invasive cervical cancer: a 25-year experience with the Miami technique // Cancer. 1993. 71. 1422–1437.
Baggish M.S., Karram M.M. Atlas of pelvic anatomy and gynecologic surgery, 2nd edition. Philadelphia: Saunders Elsevier, 2006. 1171 p.
Benedetti-Panici P., Maneschi F., D’Andrea G. et al. Early cervical carcinoma: the natural history of lymph node involvement redefined on the basis of thorough parametrectomy and giant section study // Cancer. 2000. 88. 2267–2274.
Chernofsky M.R., Felix J.C., Muderspach L.I. et al. Influence of quantity of lymph node vascular space invasion on time to recurrence in women with early-stage squamous cancer of the cervix // Gynecol. Oncol. 2006. 100. 288–293.
Chernyshova A.L. Prognosis of endometrial cancer with the evidence of metabolic syndrome: abstract of thesis…doctor of medical sciences. Tomsk, 2009. [In Russian].
Chernyshova А.L., Kolomiets L.А., Kritskaya N.G., Sukhodolo I.V. Apudocytes in proliferative processes of the endometrium // Sibirskiy nauchnyi meditsinskiy zhurnal = Siberian Scientific Medical Journal. 2005. 25. (3). 37-40. [In Russian].
Chernyshova А.L., Lyapunov А.Yu., Kolomiets L.А. et al. Identification of sentinel lymph nodes in surgical treatment of cervical cancer // Sibirskiy onkologicheskiy zhurnal = Siberian Journal of Oncology. 2012. (3). 28-33. [In Russian].
Choinzonov Е. L., Pisareva L. F., Zhuikova L. D. Cancer incidence in Tomsk region in 2004-2009. Assessment of diagnostic quality // Sibirskiy onkologicheskiy zhurnal = Siberian Journal of Oncology. 2011. (3). 29-34.
Cibula D., Abu-Rustum N.R. Pelvic lymphadenectomy in cervical cancer-surgical anatomy and proposal for a new classification system // Gynecol. Oncol. 2010. 116. 33–37.
Cibula D., Velechovska P., Sláma J. et al. Late morbidity following nerve-sparing radical hysterectomy // Gynecol. Oncol. 2010. 116. 506–511.
Courtney M. Surgery versus chemoradiation as first line therapy for stage IB2 cervical cancer. Abstracts of the 41st Annual Meeting on Women’s Cancer of the Society of Gynecologic Oncologists. March 10–17, 2010. San Francisco, California, USA // Gynecol. Oncol. 2010. 116. (Suppl. 3). S2–S169.
Covens A., Rosen B., Murphy J. et al. How important is removal of the parametrium at surgery for carcinoma of the cervix? // Gynecol. Oncol. 2002. 84. 145–149.
Darlin L., Persson J., Bossmar T. The sentinel node concept in early cervical cancer performs well in tumors smaller than 2 cm // Gynecol. Oncol. 2010, 117(2):266-9.
Diaz J.P., Sonoda Y., Leitao M.M. Oncologic outcome of fertility-sparing radical trachelectomy versus radical hysterectomy for stage IB1 cervical carcinoma // Gynecol. Oncol. 2008. 111. (2). 255-260.
Du X.L., Sheng X.G., Jiang T. et al. Sentinel lymph node biopsy as guidance for radical trachelectomy in young patients with early stage cervical cancer // BMC Cancer. 2011. 11. 157.
Eiriksson L.R., Covens A. Sentinel lymph node mapping in cervical cancer: the future? // BJOG. 2012. 119. (2). 129-133.
Fader A.N., Edwards R.P., Cost M. Sentinel lymph node biopsy in early-stage cervical cancer: utility of intraoperative versus postoperative assessment // Gynecol. Oncol. 2008. 111. (1). 13-17.
Hazewinkel M.H., Sprangers M.A., van der Velden J. et al. Long-term cervical cancer survivors suffer from pelvic floor symptoms: across-sectional matched cohort study // Gynecol. Oncol. 2010. 117. 281–286.
Hertel H., Köhler C., Grund D. Association of Gynecologic Oncologists (AGO): Radical vaginal trachelectomy (RVT) combined with laparoscopic pelvic lymphadenectomy: prospective multicenter study of 100 patients with early cervical cancer // Gynecol. Oncol. 2006. 103. (2). 506-511.
Höckel M., Horn L.C., Manthey N. et al. Resection of the embryologically defined uterovaginal (Müllerian) compartment and pelvic control in patients with cervical cancer: a prospective analysis // Lancet Oncol. 2009. 10. 683–692.
Kara P.P., Ayhan A., Caner B. Sentinel lymph node detection in early stage cervical cancer: a prospective study comparing preoperative lymphoscintigraphy, intraoperative gamma probe, and blue dye // Ann. Nucl. Med. 2008. 22. (6). 487-494.
Kondakova I.V., Spirina L.V., Shashova Е.Е. et al. Proteasome activity in tumors of the female reproductive system // Rus. J. Bioorg. Chem. 2012. 38. (1). 89-92. [In Russian].
Landoni F., Maneo A., Colombo A. et al. Randomised study of radical surgery versus radiotherapy for stage I/b-II/a cervical cancer // Lancet. 1997. 350. 535–540.
Landoni F., Maneo A., Zapardiel I. et al. Class I versus class III radical hysterectomy in stage IB1-IIA cervical cancer. A prospective randomized study // EJSO. 2012. 38. 203–209.
Niikura H, Okamura C, Akahira J. Sentinel lymph node detection in early cervical cancer with combination 99mTc phytate and patent blue // Gynecol. Oncol. 2004. 94. 528-532.
Ogawa S, Kobayashi H, Amada S. Sentinel node detection with (99m)Tc phytate alone is satisfactory for cervical cancer patients undergoing radical hysterectomy and pelvic lymphadenectomy // Int. J. Clin. Oncol. 2010. 15. (1). 52-58.
Palfalvi L., Ungar L. Laterally extended parametrectomy (LEP), the technique for radical pelvic side wall dissection: Feasibility, technique and results // Int. J. Gynecol. Cancer. 2003. 13. 914–917.
Piver M.S., Rutledge F., Smith J.P. Five classes of extended hysterectomy for women with cervical cancer // Obstet. Gynecol. 1993. 44. 265–272.
Semiglazov V.F. Novel approaches to organ-preserving surgery for cancer // Meditsinskiy vestnik = Medical herald. 2009. (35). 12-24. [In Russian].
Seong S.J., Park H., Yang K.M. Detection of sentinel lymph nodes in patients with early stage cervical cancer // J. Korean Med. Sci. 2007. 22. (1). 105-109.
Spirina L.V., Kondakova I.V., Kolomiets L.А. et al. Proteasome activity and their subunit composition in endometrial hyperplasia and endometrial cancer // Opukholi zhenskoy reproduktivnoy sistemy = Tumors of female reproductive system. 2011. (4). 64-67. [In Russian].
Tarnai L., Ungár L., Pálfalvi L. et al. Femoral artery embolism in patients undergoing a laterally extended parametrectomy (LEP) procedure // Eur. J. Gynaecol. Oncol. 2011. 32. 401–402.
Undurraga M., Loubeyre P., Dubuisson J.B. et al. Early-stage cervical cancer: is surgery better than radiotherapy? // Expert Rev. Anticancer Ther. 2010. 10. 451–460.
Ungar L., Nechushkina B.М. Why should we perform extended surgeries for cervical cancer? // Sibirskiy onkologicheskiy zhurnal = Siberian Journal of Oncology. 2013. (3). 5-12. [In Russian].
Ungar L., Palfalvi L. Surgical treatment of lymph node metastases n stage IB cervical cancer: the laterally extended parametrectomy (LEP) procedure // Int. J. Gynecol. Cancer. 2003. 13. 647–651.
Wang S.S., Sherman M.E., Silverberg S.G. et al. Pathological characteristics f cervical adenocarcinoma in a multicenter US-based study // Gynecol. Oncol. 2006. 103. 541–546.
Wertheim E. The extended abdominal operation for carcinoma uteri (based on 500 operative cases) // Am. J. Obstet. Dis. Women Child. 1912. 66. 169–232.
Yamashita T, Katayama H, Kato Y. Management of pelvic lymph nodes by sentinel node navigation surgery in the treatment of invasive cervical cancer // Int. J. Gynecol. Cancer. 2009. 19. (6). 1113-1118.
Chernyshova A.L. – doctor of medical sciences, leading researcher of department for genecology, e-mail: alacher@list.ru
Kolomiets L.A. – professor, head of department for gynecology
Krasilnikov S.E. – doctor of medical sciences, professor, head of department for gynecology