Author Affiliations1Research Institute of Biochemistry, 630117, Novosibirsk, Timakov str., 2
2Institute of Biochemistry, 630117, Novosibirsk, Timakov str., 2
3Research Institute of Biochemistry, 630117, Novosibirsk, Timakov str., 2
- .Karavaev V.S., Ryabchenko A.V., Beklemishev A.B. Enzyme immunoassay-based analysis of OspC recombinant proteins from Borrelia garinii and Borrelia afzelii isolated in West Siberia / Zhurnal mikrobiologii, epidemiologii i immunobiologii = Journal of microbiology, epidemiology and immunobiology. 2010. (1). 20-23. [In Russian].
2. Karavaev V.S., Genina E.S., Ryabchenko A.V., Beklemishev A.B.. The significance of the recombinant proteins isolates Western Siberian of Borrelia burgdorferi s.l. for serodiagnosis of Ixodes tick borne borreliosis / Klinicheskaya laboratornaya diagnostika = Clinical laboratory diagnostics. 2014. (6). 44-48. [In Russian].
3. Karavaev V.S., Ryabchenko A.V., Beklemishev A.B. Construction of E. coli strain - producer of chimeric polypeptide based on OspC from Siberian isolates of Borrelia afzelii and Borrelia garinii, and evaluation of antigenic activity of recombinant chimera / Mezhdunarodnyy zhurnal prikladnykh i fundamental'nykh issledovaniy = International journal of applied and basic research. 2015. (11-14). 534-537. [In Russian].
4. Manzenyuk I.N., Manzenyuk O.J. Lyme borreliosis (Lyme disease). Koltsovo, 2005. 85 p. [In Russian].
5. Patent № 2514230 RF. Recombinant chimeric polypeptides bearing epitopes of different immunodominant protein complex spirochete Borrelia burgdorferi sensu lato and a method of diagnosing Ixodes tick borreliosis / Beklemishev A.B., Ryabchenko A.V., Karavaev V.S.; published 03.03.2014. [In Russian].
6. Ryabchenko A.V., Karavaev V.S., Beklemishev A.B. Comparative structural and immunochemical analysis of recombinant OspC antigens of Novosibirsk Borrelia garinii and Borrelia afzelii isolates // Byulleten' Sibirskogo otdeleniya Rossiyskoy akademii meditsinskikh nauk = Bulletin of Siberian Branch of Russian Academy of Medical Sciences. 2010. (2). 6–12. [In Russian].
7. Fomenko N.V., Melnikova O.V., Chernousova N.Y., Epichina T.I.. Detection of antibodies to Borrelia burgdorferi complex sensu.lato // Byulleten' sibirskoy meditsiny = Bulletin of Siberian medicine. 2008. (Suppl. 1). 78-84. [In Russian]
8. Baranova E., Solov'ev P., Panfertsev E. et al. Rational design of antigens to improve the serodiagnosis of tick-borne borreliosis in central regions of Russia // Adv. Exp. Med. Biol. 2014. 807. 9-21.
9. Gomes-Solecki M.J., Dunn J.J., Luft B.J. et al. Recombinant chimeric Borrelia proteins for diagnosis of Lyme disease // J. Clin. Microbiol. 2000. 38. (7). 2530-2535.
10. Kenedy M.R., Lenhart T.R., Akins D.R. The role of Borrelia burgdorferi outer surface proteins // FEMS Immunol. Med. Microbiol. 2012. 66. (1). 1-19.
11. Verma A., Brissette C.A., Bowman A., Stevenson B. Borrelia burgdorferi BmpA is a laminin-binding protein // Infect. Immun. 2009. 77. (11). 4940-4946.
12. Wilske B.V., Fingerle U., Schulte-Spechtel U. Microbiological and serological diagnosis of Lyme borreliosis // FEMS Immunol. Med. Microbiol. 2007. 49. (1). 13-21.
About Authors (Correspondence):
Karavaev V.S. – candidate of medical sciences, leading researcher of laboratory for genetic engineering, e-mail: v_karavaev1@mail.ru
Ryabchenko A.V. – candidate of biology sciences, senior researcher of laboratory for medical biotechnology, e-mail: borrelia@mail.ru
Beklemishev A.B. – doctor of biological sciences, head of laboratory for genetic engineering, e-mail: beklem@academ.ru