№ 5 / 2017 / 55-61

CLINICAL, PHONOENTEROGRAPHIC, ENDOSCOPIC FEATURES OF THE GASTROINTESTINAL TRACT DYSFUNCTION IN GERIATRIC PATIENTS WITH GONARTHROSIS ON THE BACKGROUND OF TYPE 2 DIABETES MELLITUS AND PROLONGED INTAKE OF NONSTEROIDAL ANTI-INFLAMMATORY DRUGS

Author: Sirota G.G.¹, Kirilina S.I.², Sirota V.S.³, Zhukov D.V.⁴, Makukha V.K.⁵, Kusainov R.K.⁶

Abstract

Objective of the study was to analyze and evaluate the clinical, phonoenterographic, endoscopic, and morphological features of the manifestation of gastrointestinal dysfunction in geriatric patients with gonarthrosis on the background of type 2 diabetes mellitus and prolonged intake of NSAIDs. Material and Methods. An observational study was performed based on clinical, endoscopic, phonoenterographic, and morphological data of 120 patients who underwent total knee replacement for arthritis. The functional state of the gastrointestinal tract was assessed on the basis of clinical, endoscopic, and morphological data. Geriatric patients have taken NSAIDs for long periods of time, and 60 of them had type 2 diabetes mellitus. Results. The estimation of the motor-evacuator function of the gastrointestinal tract was computerized based on phonoenterography findings. It revealed that the frequency, magnitude, and duration of peristaltic sounds were significantly reduced in patients with arthrosis on the background of type 2 diabetes mellitus. Conclusions. The status of patients in this population is aggravated by the presence of diabetes mellitus, which indicates a higher incidence of clinical and phonoenterographic manifestations and endoscopic and morphological changes in the mucosa of the digestive tract. It is necessary to continue the study of the structural and functional state of the gastrointestinal tract in patients with gonarthrosis on the background of type 2 diabetes mellitus to determine the tactics of rational complex therapy in the perioperative period from a perspective of the accelerated recovery program.

Key words

geriatric patients, arthrosis, NSAIDs, diabetes mellitus, gastrointestinal dysfunction, phonoenterography, peristaltic sounds

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About Authors (Correspondence):

Kirilina S.I. – doctor of medical sciences, chief researcher of the department for anesthesiology and intensive care medicine, e-mail: ksi-kln@ngs.ru

Full Text

snmzh_5-2017_sirota_i_dr.pdf

Received: 30/10/2017

Accepted: 30/10/2017