Lymphoid system - circadian temporary organization and desynchronosis

The characteristic of liver lymphatic region and lymphoid organs cells has been given at round-the-clock illumination. The stagnant phenomena, disorders of haemo- and lymphocirculation and destruction of cells of regional lymph nodes have been revealed in liver lymphatic region at these conditions. In the thymus, somatic lymphatic nodes and blood the daily rhythms of the cell content and dehydrogenase activity have been broken, in the blood and lymph node lymphocytes the ratio eu- and heterochromatin varies. These changes are associated with decrease of humoral immune response. It has been concluded that the disruption of the light mode through the mismatch of hormonal activity results in disarrangement of lymphoid system regulation. As a consequence, the diseases of lymph circulation, immune function, cell structure of lymphatic regions including liver lymphatic region are developed.

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Shurlygina A.V. – doctor of medical sciences, professor, chief researcher, e-mail: anna_v_s@mail.ru

Michurina S.V. – doctor of medical sciences, professor, chief researcher, e-mail: ad_belkin@mail.ru