The Siberian Scientific Medical Journal
 
 
№ 4 / 2014 / 81-87

The relationship of the autonomic nervous system condition with clinical and biochemical parameters in patients with arterial hypertension combined with diseases of the hepatobiliary system in the North

Author Affiliations

Abstract

110 patients with hypertension of stage II–III, I–II degree combined with hepatobiliary system disease (HBS) were examined at the Clinic of Research Center of Clinical and Experimental Medicine of SB RAMS (Novosibirsk). All patients were divided into two groups. Hypertension patients with concomitant pathology of HBS permanently residing in temperate latitudes (Novosibirsk) were assigned to the first group; patients of non-indigenous nationalities working in the industrial enterprises of Mirniy town of the Republic of Sakha (Yakutia) and residing in the North were assigned to the second group. Age surveyed ranged from 20 to 60 years. The features of change of the autonomic nervous system (ANS) state and their correlation with clinical and biochemical status were studied. More pronounced changes in the ANS state and clinical-biochemical parameters were revealed in hypertensive patients with concomitant HBS diseases living in the North. As well the higher degree relationship between clinical-biochemical parameters and spectral characteristics of heart rate were determined compared with those living in the mid-latitudes.

Key words

the North, hypertension, biochemical indices, vegetative nervous system, hepatobiliary system disease
References
About Authors (Correspondence):

Gevorgyan M.M. – candidate of biological sciences, head of the clinical and biochemical laboratory, e-mail: gevorgyanmm@ngs.ru

Nikolaev Yu.A. – doctor of medical sciences, deputy director on medical and scientific work, head of laboratory for somatic diseases pathogenesis, chief researcher, e-mail: nicol@soramn.ru

Kozaruk T.V. – physician of the clinical and biochemical laboratory

Voronina N.P. – doctor of biological sciences, physician of the clinical and biochemical laboratory

Obukhov I.V. – candidate of medical sciences, head of the functional diagnostics laboratory

Polyakov V.Ya. – doctor of medical sciences, senior researcher of laboratory for somatic diseases pathogenesis, e-mail: vpolyakov15@mail.ru

Kosheleva A.P. – researcher of laboratory for somatic diseases pathogenesis, e-mail: kuzik86@mail.ru

Full Text

Received: 09/02/2015