The Siberian Scientific Medical Journal
№ 1 / 2012 / 81-85

Advances of current oncology in the treatment of malignant head and neck tumors

Author Affiliations


The organ-preserving and reconstructive plastic surgeries elaborated at the Research Institute of Oncology SB RAMS (Tomsk, Russia) with the use of biocompatible implants, different types of radiation therapy and up–to–date anti-tumor agents have made possible to increase the survival rates with maintenance of the high level of cancer patients’ life quality. The use of titanium-nickelide implants provides the reliable restoration of removed structures, cranial cavity hermetization, decrease in the surgery length, shortening of the wound healing period, and does not influence on immediate and long-term treatment results. Biochemical TIMP-2 marker in blood serum of patients with squamous cell cancers of oral cavity and oropharynx can be used as the marker of tumor response to chemotherapy.

Key words

biocompatible implants, head and neck cancer, combined modality treatment, reconstructive-plastic surgeries
About Authors (Correspondence):

Choynzonov E.L. – professor, academician of RAMS, director

Novikov V.A. – doctor of medical science, leading researcher, e-mail:

Perelmuter V.M. – doctor of medical science, professor, head of the laboratory for pathomorphology

Balatskaya L.N. – doctor of biological science, leading researcher

Mukhamedov M.R. – doctor of medical science, leading researcher

Klisho E.V. – candidate of medical science, leading researcher

Syrkashev V.A. – resident surgeon

Avdeenko M.V. – MD PhD, researcher

Full Text

Received: 10/02/2015