Fatty acid binding protein – the serological marker of myocardial damage
Quantitative measurement of heart-type fatty acid binding protein (H-FABP) in serum, as shown by analysis of published data, allows the improvement of early laboratory diagnostics of acute myocardial infarction. H-FABP can be also successfully used as a predictor of serious complications in patients with acute coronary syndrome and for monitoring the conduct therapy. Performance evaluation studies of a novel H-FABP ELISA kit revealed that it has high sensitivity and specificity characteristics (93.9 и 90.1 % respectively), and can be recommended for widespread use in clinical laboratory diagnostics.
About Authors (Correspondence):
Salnikov A.S. - researcher of the laboratory of ELISA of hormones and tumor markers, е-mail: email@example.com
Sorokina N.N. - head of the laboratory of ELISA of hormones and tumor markers
Rukavishnikov M.Yu. - associate director
Ofitserov V.I. - doctor of biological sciences, deputy director general for science