The Siberian Scientific Medical Journal
 
 
№ 1 / 2012 / 86-92

Fatty acid binding protein – the serological marker of myocardial damage

Author Affiliations

Abstract

Quantitative measurement of heart-type fatty acid binding protein (H-FABP) in serum, as shown by analysis of published data, allows the improvement of early laboratory diagnostics of acute myocardial infarction. H-FABP can be also successfully used as a predictor of serious complications in patients with acute coronary syndrome and for monitoring the conduct therapy. Performance evaluation studies of a novel H-FABP ELISA kit revealed that it has high sensitivity and specificity characteristics (93.9 и 90.1 % respectively), and can be recommended for widespread use in clinical laboratory diagnostics.

Key words

H-FABP, cardiac biochemical markers, ELISA, clinical laboratory diagnostics, acute myocardial infarction
References
About Authors (Correspondence):

Salnikov A.S. - researcher of the laboratory of ELISA of hormones and tumor markers, е-mail: sas_salnikov@mail.ru

Sorokina N.N. - head of the laboratory of ELISA of hormones and tumor markers

Rukavishnikov M.Yu. - associate director

Ofitserov V.I. - doctor of biological sciences, deputy director general for science

Full Text

Received: 09/02/2015