Hepatocyte ploidy of the rats under the high fat diet

The ploidy of rats’ hepatocytes under the high fat diet condition has been investigated. It was shown that cellular mechanisms of regeneration on the way of hepatocytes polyploidy were performed only under the high degree of the organ damage (steatohepatitis), while there were no changes of the liver cells ploidy level under the condition of steatosis and absence of the destructive necrotic transformation of tissues.

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Karaman Yu.K. – candidate of biological sciences, senior researcher of the laboratory of biomedical researches, e-mail: karaman@inbox.ru

Gvozdenko T.A. – doctor of medical sciences, director, e-mail: vfdnz@mail.ru