The research on coagulation factors of external, internal and general mechanisms of coagulation hemostasis in children with stable arterial hypertension
Author Affiliations1Scientific Center for Problems of Family Health and Human Reproduction SB RAMS 664003, Irkutsk, Timiryazev str., 16
2Scientific Center for Problems of Family Health and Human Reproduction SB RAMS 664003, Irkutsk, Timiryazev str., 16
3Irkutsk State Medical University 664003, Irkutsk, Red Revolt str., 1
4Scientific Center for Problems of Family Health and Human Reproduction SB RAMS 664003, Irkutsk, Timiryazev str., 16
Abstract
This article presents a study on factors of external, internal and general mechanisms of coagulation hemostasis in children with stable arterial hypertension. The significant increase of activity factors VIII, XI, X, V, decrease of activity factor XII, as well as increase of the factor Willebranda` activity and content in children with stable hypertension have been revealed, that testify to latent hypercoagulation. The increase of factor VIII activity was observed in 29,7 %, factor XI – 15,6 %, X – 12,5 %, V – 14,1 %, the decrease in factor XII – 12,5 %, the increase of factor Willebranda` activity and content – in 37,5 % of patients with stable arterial hypertension.
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About Authors (Correspondence):
Gomellya M.V. – candidate of medical sciences, researcher of the laboratory of environmental pediatrics and rehabilitation, assistant of the chair for pediatrics of the faculty for advanced training and occupational retraining, e-mail: marina_gomellya@mail.ru
Dolgikh V.V. – doctor of medical sciences, professor, the deputy director on scientific researches
Philippov E.S. – doctor of medical sciences, professor, head of the chair for pediatrics of the faculty for advanced training and occupational retraining
Rychkova L.V. – doctor of medical sciences, the head of the department of environmental pediatrics
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