The Siberian Scientific Medical Journal
№ 2 / 2012 / 67-73

Immunometabolic peculiarities of the comorbid course of the chronic cholecystitis and metabolic syndrome

Author Affiliations


Present research is aimed at study of the immunometabolic peculiarities of the cormobid chronic cholecystitis and metabolic syndrome. Totally 127 patients with chronic cholecystitis were examined, 77 patients had metabolic syndrome. The peculiarity of the comorbid metabolic syndrome and chronic cholecystitis is a hyperactivity of the systemic inflammation, which is reflected in increase of the production of TNF-α proinflammatory cytokine, TNF-α soluble receptor and evident changes in all components of the immune system.

Key words

immunity, metabolic syndrome, chronic cholecystitis, cytokines
About Authors (Correspondence):

Yurenko A.V. – head of the therapeutic department, e-mail:

Antonyuk M.V. – doctor of medical sciences, head of the laboratory for rehabilitative treatment, e-mail:

Dem’yanenko N.B. – doctor-laboratory assistant of the clinical-diagnostic laboratory,  e-mail

Shchedrina O.B. – doctor-laboratory assistant of the clinical-diagnostic laboratory, e-mail:

Full Text

Received: 10/02/2015