The Siberian Scientific Medical Journal
 
 
№ 2 / 2012 / 80-85

Influence of malnutrition on hormonal response to cardiosurgery in patients with acquired heart disease

Author Affiliations

Abstract

Goal was to study the effects of malnutrition on hormone response to cardiosurgery in patients with acquired heart disease. Material and methods: 123 patients with acquired heart disease operated on cardiopulmonary bypass were examined. Serum albumin level, total lymphocyte count, cortisol and insulin were measured at three study phases (baseline, the end of operation, and 1st day after surgery). Results and discussion: Classic hormonal response on cardiosurgery, with characterized in increased cortisol at the end of operation and at the 1st day after operation, and increased level of insulin at the 1st day after operation was not found in patients with acquired heart disease with baseline serum albumin level below 40 g/L. It testifies to compensatory mechanisms exhaustion.

Key words

insulin, cortisol, malnutrition, acquired heart disease
References
About Authors (Correspondence):

Subbotovskaya A.I. – junior researcher of the group of clinical immunology of clinic-biochemical laboratory, e-mail: rubanova_ai@mail/ru

Knyaz’kova L.G. – candidate of biological sciences, leading researcher of biochemical group of clinic-biochemical laboratory, e-mail: klg5151@mail.ru

Shilova A.N. – doctor of medical sciences, head of clinic-biochemical laboratory, e-mail: shilovaanna77@mail.ru

Lomivorotov V.V. – doctor of medical sciences, head of laboratory of anesthesiology and intensive care unit, e-mail: vvlom@mail.ru

Subbotovskiy A.P. – resident of laboratory of anesthesiology and intensive care unit, e-mail: subbotovsky_ap@mail.ru

Sergeevichev D.S. – candidate of biological sciences, head of laboratory of experimental surgery and morphology, e-mail: d_sergeevichev@nricp.ru

Efremov S.M. – candidate of medical sciences, senior researcher of laboratory of anesthesiology and intensive care unit, e-mail: sergefremov@mail.ru

Full Text

Received: 10/02/2015