Natriuretic peptides in patients with metabolic syndrom
Author Affiliations1Vladivostok Branch of the Far Eastern Scientifi c Center of Physiology and Pathology of Res-piration of the SB RAMS – Institute of Medical Climatology and Rehabilitation 690105, Vla-divostok, Russkaya str., 73g
2Vladivostok Branch of the Far Eastern Scientifi c Center of Physiology and Pathology of Res-piration of the SB RAMS – Institute of Medical Climatology and Rehabilitation 690105, Vla-divostok, Russkaya str., 73g
3Vladivostok Branch of the Far Eastern Scientifi c Center of Physiology and Pathology of Res-piration of the SB RAMS – Institute of Medical Climatology and Rehabilitation 690105, Vla-divostok, Russkaya str., 73g
4Vladivostok Branch of the Far Eastern Scientifi c Center of Physiology and Pathology of Res-piration of the SB RAMS – Institute of Medical Climatology and Rehabilitation 690105, Vla-divostok, Russkaya str., 73g
Abstract
Present research aimed at study of the atrial (proANP) and brain natriuretic (NT-proBNP) peptide levels in blood plasma of the patients with metabolic syndrome. 52 patients have been examined; an observation group was composed of 40 patients with metabolic syndrome, and a control group 12 was composed of conventionally healthy people. The NT-proBNP increase of 20 % (p < 0.05) and proANP of 67.8 % (p < 0.05) have been revealed in blood plasma of the patients with metabolic syndrome. A strong correlation between atrium and brain natriuretic peptides in plasma and insulin, insulin resistance index have been established that allows considering natriuretic peptides as the markers of the early diagnostics of metabolic syndrome.
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About Authors (Correspondence):
Gvozdenko T.A. – doctor of medical sciences, director, e-mail: vfdnz@mail.ru
Simonova I.N. – candidate of medical sciences, junior researcher of the laboratory of rehabilitative treatment, e-mail: SimonovaI68@mail. ru
Khodosova K.K. – head of laboratory for clinical and laboratory diagnosis, e-mail: kira_hodosova@mail.ru
Veremchuk L.V. – doctor of biological sciences, leading researcher of the laboratory for medical and informational technologies, e-mail: Veremchuk@mail.primorye.ru
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