Neuroautonomic risk factors for the labor abnormalities on the data of maternal cardiorhythm variability
Responsive changes of the heart rate variability (HRV) indices were analyzed in women with normal pregnancy outcome (NP, n = 97) and with the labor abnormalities (LA, n = 137) under mental (calculation in mind) and respiratory (deep breathing with a voluntary periodicity) loading tests. Signifi cant differences were found between NP and LA groups concerning vago-sympathetic index (as a ratio between high and very low HRV spectral components, VSI) and a parameter of detrended fl uctuation analysis (DFA) of maternal cardiac rhythm against respiratory probe in subgroups of women with initially high barorefl ex (HB) and sympathetic (HS) activity: LA (HB): increase of VSI +11 %; NP (HB): decrease of VSI–10 %, p < 0.05; LA (HS): increase of VSI +33 %; NP (HS): decrease of VSI–3 %, p < 0.10). LA (HB): decrease of DFA–7 %; NP (HB): increase of DFA +8 %, p < 0.10; LA (HS): decrease of DFA -10 %; NP (HS): increase of DFA +13 %, p < 0.001). It has been concluded that maternal heart rate variability under condition of respiratory loading test is the valuable criteria for prediction of the labor abnormalities at early gestational terms (in mid-pregnancy).
About Authors (Correspondence):
Kleshchenogov S.A. – candidate of medical sciences, senior researcher of the laboratory of physiology, e-mail: firstname.lastname@example.org