Ontogenetic and gender features of cytokine profile of rat lymph and blood serum
Abstract
The investigation of lymph cellular composition and cytokine profile (IL-1α, IL-1β, IL -2, IL -4, IL -6, IL -10, GM-CSF, interferon-γ, TNFα,) of lymph, serum and conditioned medium of lymph cells of Wistar rats of 3 and 9 months age in norm have been carried out. The age and gender differences between the concentration of pro-and anti-inflammatory cytokines in the lymph and blood serum have been revealed. It was found that the concentrations of cytokines of investigated l Wistar rats` lymph were significantly higher compared to serum.
Key words
ReferencesPoveshchenko A.F. – doctor of medical sciences, head of the laboratory, e-mail: poveshchenkoa200@mail.ru
Orlov N.B. – candidate of medical sciences, leading researcher, e-mail: nbo@ngs.ru
Kazakov O.V. – candidate of biological science, leading researcher, e-mail: kazakoff_oleg@mail.ru
Poveshchenko O.V. – candidate of medical sciences, head of the laboratory, e-mail: PoveschenkoOV@yandex.ru
Chepik V.I. – junior researcher
Kim I.I. – researcher, e-mail: kii5@yandex.ru
Bondarenko N.A. – postgraduate student, e-mail: bond802888@yandex.ru
Miller T.V. – postgraduate student, e-mail: tmw87@mail.ru
Strunkin D.N. – candidate of medical sciences, researcher
Uzvarik L.M. – junior researcher, e-mail: lubluba@yandex.ru
Kabakov A.V. – postgraduate student, e-mail: Doctor03-85@ngs.ru
Moskalchuk T.V. – postgraduate student, e-mail: reitert@mail.ru
Konenkov V.I. – doctor of medical sciences, academician of RAS, director, e-mail: konenkov@soramn.ru
