№ 4 / 2014 / 73-80

Influence of gender characteristics on 1 year outcomes after coronary artery bypass graft

Author: Sumin A.N.¹, Korok E.V.², Gayfulin R.A.³, Ivanov S.V.⁴, Barbarash O.L.⁵

Abstract

Objective: To assess the influence of gender characteristics on the incidence of PolyVD and on 1 year outcomes after CABG in CAD patients. Material and methods. 662 patients underwent elective CABG were enrolled in the study. The outcomes were assessed 1 year after the procedure. All the patients were divided into 2 groups: Group 1 – females (n = 130 ), Group 2 – males (n = 532). Results. The incidence of PolyVD was equal in both groups – 25.4 % and 24.8 % (p = 0.892 ). Lesions of the brachiocephalic arteries prevailed in the female group (18.5 % vs. 12.4 %, p = 0.070 ), while lesions of the abdominal aorta and lower extremity arteries were more likely found in the male group (6.9 % vs. 14.9 %, p = 0.017). The total number of cardiovascular events within a year was 10.8 % for females and 7.3 % for males (p = 0.19). Ischemic stroke was more common among females ( 4.6 % vs. 1.1 %, p = 0.007). The independent predictors of cardiovascular mortality were as following: decrease of left ventricular ejection fraction (p = 0.04), acute renal failure in the postoperative period (p = 0.01 ), myocardial infarction – multivessel coronary artery disease (p = 0.02); stroke – females (p = 0.03 ), diabetes (p = 0.03) , PolyVD (p = 0.02). Conclusion. Carotid artery stenosis and a stroke following CABG (p = 0.007) were more likely found in females. Female gender, diabetes mellitus and PolyVD appeared to be independent predictors of stroke within a year following CABG.

Key words

gender features, coronary artery bypass grafting, polyvascular disease

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About Authors (Correspondence):

Sumin A.N. – doctor of medical sciences, head of multifocal atherosclerosis department, e-mail: an_sumin@mail.ru

Korok E.V. – researcher of the laboratory of blood circulation pathology, e-mail: korok-82@mail.ru

Gayfulin R.A. – candidate of medical sciences, researcher of the laboratory of interventional diagnosis and treatment methods, e-mail: rus_gayf@mail.ru

Ivanov S.V. – doctor of medical sciences, head of laboratory of reconstructive surgery of multifocal atherosclerosis, e-mail: ivansv@cardio.kem.ru

Barbarash O.L. – doctor of medical sciences, professor, director, e-mail: olb61@mail.ru

Full Text

12-4-2014.pdf

Received: 09/02/2015