The Siberian Scientific Medical Journal
№ 2 / 2016 / 74-78

The experience of hospital thrombolytic therapy of st-segment elevation myocardial infarction in regional vascular center

Author Affiliations


Objective. The analysis of some cases of hospital thrombolytic therapy in the regional vascular center. Material and methods. The capacity of reperfusion therapy in 2014, including hospital pharmacological therapy, is presented. Results. 436 (67.9 %) patients have had reperfusion therapy: percutaneous coronary interventions (PCI) in isolation – 326 (50.8  %), only thrombolytic therapy – 36 (5.6  %), pharmaco-invasive method – 74 (11.5  %). Thrombolytic therapy was performed in 110 (17.1  %) cases, 98 (15.2  %) from them - by ambulance teams. The need for hospital thrombolytic therapy occurred in 12 cases (1.9  %). In 9 cases, the main reason was impossibility to do primary PCI due to the occupancy of the room for angiography. In 8 cases thrombolytic therapy was performed by a recombinant protein containing the amino acid sequence of staphylokinase (Fortelyzin®), and it was effective. All patients have had successful PCI. Conclusions. In conditions of our regional vascular centre, we used thrombolytic therapy as a forced measure due to simple circumstances (the patient’s refusal of coronary interventions or allergic to contrast) or high occupancy of the angiographic operating room. The results of the administration of Russian thrombolytic agent Fortelyzin® have left a positive impression. Further accumulation of experience will determine the place of this medication in clinical practice.

Key words

hospital thrombolytic therapy, acute myocardial infarction, the Regional Vascular Center, reperfusion therapy, percutaneous coronary intervention
About Authors (Correspondence):

Kireev K.A. – candidate of medical sciences, endovascular physician for diagnosis and treatment of department of endovascular diagnostic and treatment methods, e-mail:

Krasnopeev A.V. – physician-resuscitator of department of anesthesiology and intensive care, e-mail:

Full Text

Received: 19/05/2016