BRAIN BIOELECTRIC ACTIVITY CHANGES ASSOCIATED WITH THE LONG-TERM POSTOPERATIVE COGNITIVE DYSFUNCTION IN PATIENTS AFTER CORONARY ARTERY BYPASS GRAFTING
The purpose of the study was to investigate the changes in the bioelectric activity of the cerebral cortex associated with long-term postoperative cognitive dysfunction (POCD) 1 year follow-up after coronary artery bypass grafting (CABG). Material and methods. The study included 65 patients with coronary artery disease (CAD). The patients were divided into two groups depending on the presence of long-term POCD: with the presence of cognitive impairment (n = 36, mean age 58.1 ± 4.40 years) and without it (n = 29, mean age 55.6 ± 4.93 years). All patients underwent neuropsychological and electroencephalographic (EEG) study 3–5 days before surgery, at 7–10 days and 1 year after CABG. Results and discussion. It was found that the factors associated with developing long-term POCD after CABG were: older age, the presence of early POCD, as well as higher values teta1 rhythm power in the left occipital cortex, while the similar changes in the right occipital cortex reduced the likelihood of developing long-term POCD. It is assumed that the perioperative factors cause long-term cognitive deficit, but could be not excluded the effect of progressive atherosclerotic cerebrovascular disease in these patients. The diagnostic significance of quantitative EEG was shown in the assessment of long-term neurological outcomes in cardiac patients.
About Authors (Correspondence):
Tarasova I.V. – candidate of medical sciences, leading researcher of laboratory for ultrasound and electrophysiological methods FSBSI RI SICVD, e-mail: firstname.lastname@example.org