№ 4 / 2014 / 88-96

Correlation of borderline values of cardio-vascular ankle indexes with clinical and instrumental parameters in patients with coronary heart disease

Author: Sumin A.N.¹, Shcheglova A.V², Fedorova N.V.³, Zhuchkova E.A.⁴, Barbarash O.L.⁵

Abstract

The purpose of the study was to examine the interconnection between boundary values of cardio-ankle vascular index and clinical and instrumental parameters in patients with coronary artery disease. 356 people aged 33–81 years old scheduled for coronary artery bypass grafting were examined in the Clinic. The patients underwent peripheral arterial stiffness assessment of cardio-ankle vascular index with an instrument VaSera VS-1000. Three groups were defined: I group (n = 125) – patients with the value of cardio-ankle vascular index < 8.0, II group (n = 106) – patients with the value of cardio-ankle vascular index 8.0–9.0, and group III (n = 125) – patients with the index value > 9.0. These groups were compared by the key demographic, anthropometric indicators, by the presence of atherosclerotic risk factors, comorbidities, the prevalence of atherothrombotic events in history, according to laboratory and instrumental examination. It has been shown that patients with coronary artery disease with borderline values by the prevalence of risk factors occupy the intermediate position compared with patients with normal and pathological values of cardio-ankle vascular index. In patients with borderline and pathological index values the stenosis of the carotid arteries have been more often revealed ≥ 30 %. At the same time, the prevalence of coronary atherosclerosis and structural indicators of echocardiography did not differ in the three groups studied.

Key words

coronary artery bypass grafting, coronary atherosclerosis, cardio-ankle vascular index

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About Authors (Correspondence):

Sumin A.N. – doctor of medical sciences, head of the department of multifocal atherosclerosis,

e-mail: an_sumin@mail.ru

Shcheglova A.V. – junior researcher of laboratory of blood circulation pathology, e-mail: nura.karpovitch@yandex.ru

Fedorova N.V. – laboratory researcher of laboratory of blood circulation pathology, e-mail: fedonv@cardio.kem.ru

Zhuchkova E.A. – junior researcher of laboratory of ultrasonic and electrophysiological methods of diagnosis, e-mail: zhucea@cardio.kem.ru

Barbarash O.L. – doctor of medical sciences, professor, director, e-mail: olb61@mail.ru

Full Text

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Received: 09/02/2015