The Siberian Scientific Medical Journal
 
 
№ 2 / 2012 / 61-66

Composition of blood free and esterified fatty acids under the forming of metabolic syndrome

Author Affiliations

Abstract

The composition of plasma fatty acids, erythrocytes lipids, and the level of oxylipins in the blood serum of the patients with metabolic syndrome have been investigated. The increase of the polyunsaturated fatty acids level in blood plasma was detected while their simultaneous decrease in erythrocytes; high content of the leukotriene B4, thromboxane A2, 6-keto-prostaglandine-Fwas registered in the blood serum. The revealed modification of the composition of free and esterified fatty acids in blood plasma and cells, disorder of vasoactive and anti-inflammatory oxylipins synthesis are important pathogenetic link of metabolic syndrome development.

Key words

fatty acids, metabolic syndrome, oxylipins
References
About Authors (Correspondence):

Novgorodtseva T.P. – doctor of biological sciences, professor, deputy director for scientific work, head of the laboratory of biomedical researches, e-mail: curdeal@mail.ru

Karaman Yu.K. – candidate of biological sciences, senior researcher of the laboratory of biomedical researches, e-mail: karaman@inbox.ru

Zhukova N.V. – doctor of biological sciences, associated professor, senior researcher of the laboratory for comparative biochemistry, e-mail: nzhukova35@list.ru

Lobanova E.G. – candidate of medical sciences, researcher of the laboratory of biomedical researches, e-mail: isachenko1@yandex.ru

Antonyuk M.V. – doctor of medical sciences, head of the laboratory of the rehabilitative treatment, e-mail: antonyukm@mail.ru

Full Text

Received: 09/02/2015