The Siberian Scientific Medical Journal
 
 
№ 4 / 2014 / 5-10

The effects of fibronectin on the migration activity of endothelial cell line EA.Hy926

Author Affiliations

Abstract

Studying of migratory potential of endothelial cells line EA.Hy926 in the direction of gradient of cytokines concentration and growth factors and fibronectin influence on it was the research objective. It has been revealed that erythropoietin, tumor necrosis factor -alpha and vascular endothelial growth factor stimulate the migratory potential of EA.Hy926 in the first hours of the experiment. Expressiveness of migratory in the direction of cytokines concentration and growth factors depends on conditioning with fibronectin.

Key words

migration, growth factors, fibronectin
References
About Authors (Correspondence):

Lykov A.P. – candidate of medical sciences, leading researcher of laboratory of lymphotropic therapy and lymphodiagnostics, e-mail: lykovalex@freemail.ru

Bondarenko N.A. – postgraduate student of laboratory of lymphotropic therapy and lymphodiagnostics, e-mail: bond802888@yandex.ru

Kim I.I. – researcher of laboratory of lymphotropic therapy and lymphodiagnostics, e-mail: kii5@yandex.ru

Poveshchenko O.V. – candidate of medical sciences, head of the laboratory of lymphotropic therapy and lymphodiagnostics, e-mail: poveschenkoov@yandex.ru

Poveshchenko A.F. – doctor of medical sciences, head of the laboratory of physiology of the protective system, e-mail: poveshchenkoa200@mail.ru

Konenkov V.I. – academician of RAS, doctor of medical sciences, director, e-mail: lymphology@soramn.ru

Full Text

Received: 08/02/2015